Aflatoxin Cause DNA Damage

Aflatoxin Cause DNA Damage

Aflatoxins are food-borne secondary toxic fungal metabolites produced during the growth of Aspergillus flavus and A. parasiticus. Aflatoxins are well known hepatotoxic, hepatocarcinogenic and mutagenic agents. These effects are mainly due to adduct formation with DNA, RNA and protein. In addition, it also causes lipid peroxidation as well as oxidative damage to DNA. AFB1 possess genotoxic poten...

ferula assafoetida latex can cause damage to bacterial dna

asafoetida is the dried latex exuded from the living underground rhizome or tap root of ferula assafoetida. antibacterial characteristic of asafoetida was shown using the circular zone diameter of bacterial growth inhibition by disk-diffusion method on two gram positive and three gram negative bacteria. then, the bacterial genomic dna damage, induced by f. assafoetida latex, was demonstrated us...

Aflatoxin B1-Induced Developmental and DNA Damage in Caenorhabditis elegans

Aflatoxin B₁ (AFB₁) is a ubiquitous mycotoxin produced by toxicogenic Aspergillus species. AFB₁ has been reported to cause serious adverse health effects, such as cancers and abnormal development and reproduction, in animals and humans. AFB₁ is also a potent genotoxic mutagen that causes DNA damage in vitro and in vivo. However, the link between DNA damage and abnormal development and reproduct...

heteroalkyl oxime derivative can cause damage to bacterial dna

the present study aimed to evaluate the antimicrobial activity of a hetroalkyl oximec synthetic compoundderivative (benzophenone o-4-bromoethyl oxime) against two gram positive and three gram negative bacteria.the antibacterial characteristic of this compound was shown using the circular zone diameter of bacterial growthinhibition by disk-diffusion method. in addition, the random amplified poly...

Radiation track and DNA damage